Chigra Bio · Belgrade

Your body works for you. Help it stay that way.

Small, consistent steps, grounded in science and tailored to you. Only what you really need — and if you don't need anything, we'll tell you.

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Science. Care. You.Prevention · Measurement · Individual protocols
01 — Who we are

A science-based approach to prevention

Chigra Bio is a start-up founded by university professors of clinical pharmacy and medical biochemistry and developed in collaboration with practising clinicians, with the aim of providing personalised preventive services that preserve and improve health.

We combine the measurement of biomarker concentrations and, where justified, additional epigenetic testing with multidisciplinary interpretation, and translate the findings into personalised supplementation and nutrition protocols that we monitor, reassess and adjust over time.

Supplementation only when it is clearly indicated. Each recommendation is held to the standard we apply to pharmacotherapy — a defined indication, supporting evidence, an individual dose and duration, a check for interactions and a planned reassessment. When supplementation is not needed, we say so.
A couple laughing together in a hammock in the sun
02 — The case for prevention

Why prevention, and why now

43M

deaths from non-communicable diseases worldwide in 2021

75%

of all deaths not related to the pandemic

18M

of those deaths occurred before the age of 70

A substantial share of these deaths is linked to modifiable risk factors such as poor diet, physical inactivity, smoking and harmful alcohol use, whose negative effects on health develop gradually, over years. Medicine is exceptionally good at treating established disease, yet it has far fewer structured tools for the long interval before signs and symptoms of disease appear. That interval is where structured, individualised prevention adds value.

Built on P4 medicine

P1

Predictive

Identify risk as early as the data allow.

P2

Preventive

Act on modifiable factors before they disturb the body's balance.

P3

Personalised

Fit every recommendation to the individual's data and context.

P4

Participatory

Engage the client in understanding results, recommendations and follow-up.

Sources: World Health Organization, Noncommunicable diseases fact sheet (2025). Emmert-Streib F, et al. The role of digital twins in P4 medicine: A paradigm for modern healthcare. npj Digit Med. 2025;8(1):735.

03 — Our clinical standard

Supplementation, held to a therapeutic standard

Supplements are often taken on one's own initiative, without a prior assessment of whether their use is justified, the appropriate dose, the duration of supplementation or possible interactions with medicines. That is why, before recommending supplementation, our team works through seven key questions.

  1. 01Do you really need this supplement?
  2. 02Why this supplement, and in which form?
  3. 03Is the dose tailored to you?
  4. 04How long should you take it?
  5. 05Is it safe to combine with the medicines and other supplements you take?
  6. 06How do we know it is really helping you?
  7. 07When should the protocol change or stop?

Four foundations of healthy living

Sleep
Physical activity
Nutrition
Stress & social connection

Irreplaceable foundations of good health. Every protocol we write starts from these four and builds on them.

Chigra Bio does not diagnose, treat or replace medical care, and does not alter prescribed therapy. Clinically significant findings are referred back to the treating physician or to the appropriate specialist.

Programmes

Two programmes, one standard

A biomarker-led or an epigenetic assessment — always with expert interpretation, a personalised protocol and follow-up.

Programme 01

Chigra Panel

A biomarker-led assessment with multidisciplinary interpretation, a personalised protocol and one month of structured follow-up.

A cyclist on a misty meadow at sunrise

What the programme includes

01

Health questionnaire

Health status, medicines, current supplements, lifestyle and family history.

02

Biochemical panel

33 parameters, at a laboratory of choice or at our partner laboratory on preferential terms.

03

Expert interpretation

Results are interpreted alongside the questionnaire and any therapy the client is taking.

04

Consultation

45 minutes, in person, with at least two members of our specialist team.

05

Supplement protocol

What, in which form and dose, for how long and why — or a clear statement that nothing is needed.

06

Nutrition plan

Practical, individual dietary guidance aligned with the biochemical findings.

07

Follow-up

Support through the first month and a review consultation at one month.

08

Reassessment

Repeat measurement when indicated, to confirm the protocol is doing what it should.

Well suited to people who take supplements on their own initiative, take several medicines, or want a comprehensive, structured, data-based approach to prevention.

Programme 01 · Measurement
33parameters,
one coherent picture

The panel covers carefully selected biochemical and haematological markers that give insight into metabolic and hormonal health, the function of key organs and the overall state of the body, making it possible to recognise potential deviations and create individually tailored recommendations. Recent results from any laboratory, no older than one month, are accepted.

Laboratory of choice

The full list of analyses

All analyses on our list are required. Results must be no older than one month.

See all 33 parameters ›
Partner laboratory · DiaLab

10% off the panel

Chigra Bio clients receive a 10% discount on the panel at DiaLab.

Laboratory analyses are invoiced by the laboratory. Lipoprotein(a) concentration needs to be measured only once in a lifetime; PSA is included for men only.

Chigra Panel — list of 33 laboratory parameters

Glucose regulation

  • Glucose
  • HbA1c
  • Insulin
  • HOMA index

Lipid status

  • Triglycerides
  • Total cholesterol
  • HDL cholesterol
  • LDL cholesterol
  • Lipoprotein(a)*
  • ApoB

Kidney function and purines

  • Urea
  • Creatinine
  • Uric acid

Proteins

  • Total protein
  • Albumin

Liver

  • Total bilirubin
  • ALT (alanine aminotransferase)
  • AST (aspartate aminotransferase)
  • GGT (gamma-glutamyl transferase)

Pancreas

  • Lipase

Inflammation and cardiovascular risk

  • hsCRP
  • Homocysteine

Haematology

  • Complete blood count with differential

Thyroid

  • TSH
  • Free T4 (fT4)

Vitamins and minerals

  • Vitamin B12
  • Folic acid (folate)
  • Vitamin D (25-OH)
  • Magnesium

Iron status

  • Iron
  • TIBC
  • Ferritin

Men only

  • Total PSA†

* Lipoprotein(a) needs to be measured only once in a lifetime; if you already have a result, it need not be repeated. † PSA for men only. Results must be no older than one month. Laboratory analyses are not included in the package price and are paid to the laboratory; Chigra Bio clients receive 10% off at our partner laboratory DiaLab.

The patient pathway

  1. 1

    Questionnaire

    Online, 10–15 min

  2. 2

    Blood sample

    Lab of choice or DiaLab

  3. 3

    Interpretation

    Multidisciplinary review

  4. 4

    Consultation

    45 min, in person

  5. 5

    Protocol

    Supplements and nutrition

  6. 6

    Review

    At one month

04 — Epigenetics in brief

The measurable layer between genes and lifestyle

The DNA sequence remains largely unchanged throughout life. Epigenetic marks, above all DNA methylation at CpG sites, help regulate gene activity and change with age, but also under the influence of lifestyle and environmental factors such as diet, sleep, physical activity, stress and smoking.

Based on DNA methylation patterns, validated algorithms known as epigenetic clocks can estimate biological age from a small blood sample, and some can also estimate the current pace of biological ageing.

Genetic testing

What was inherited

A static result: essentially the same at 30 as at 60.

Epigenetic testing

How one is living

A dynamic result that responds to change and supports retesting.

Biological age by organ system

Chronological age: 45
Inflammation54
Heart52
Metabolism51
Joints50
Liver49
Lungs48
Musculoskeletal47
Immune system46
Hormones46
Blood45
Brain44
Kidneys43
Digestive42
Older than chronologicalEqual or youngerChronological ageIllustrative example.

Biological age estimates and epigenetic markers of ageing are used for prevention and monitoring. They are not diagnostic tests.

05 — Our epigenetic testing partner

TruDiagnostic

Epigenetic analysis for Chigra Epigenome is performed by TruDiagnostic, a specialised epigenetics and multi-omics company founded in 2020 in Lexington, Kentucky, USA. Its algorithms are developed with leading academic groups and published in the peer-reviewed literature.

No venepuncture. A single finger-prick capillary blood sample is collected wherever is most convenient for the client.

CLIA · CAP

CLIA-certified, CAP-accredited laboratory.

900,000+

DNA methylation sites analysed per sample.

Academic

Algorithms with Duke and Columbia (DunedinPACE), Harvard (OMICmAge) and Yale (SYMPHONYAge).

Database

Reports the world's largest private DNA methylation database.

What the report covers

  • Biological vs chronological age
  • Immune cell composition
  • Pace of ageing (DunedinPACE)
  • Telomere length estimate
  • Ageing of organ systems
  • 100+ markers of metabolic and hormonal health, plus markers of senescence, the inflammasome and chemical exposure

Sources: trudiagnostic.com; Rupa Health laboratory profile.

Programme 02

Chigra Epigenome

An epigenetic assessment of biological ageing, with expert interpretation, a personalised protocol and the option to retest.

A woman in soft daylight looking aside and smiling

What the programme includes

01

Health questionnaire

Health status, medicines, current supplements, lifestyle and family history.

02

Sampling, anywhere

A capillary blood sample is taken by trained partner-laboratory technicians at our office or at an address that suits the client.

03

Epigenetic analysis

TruAge and TruHealth, performed by TruDiagnostic.

04

Expert interpretation

Read alongside the questionnaire, medicines and any available biochemistry.

05

Consultation

Results explained in plain language; priorities agreed together.

06

Supplement protocol

Based on the interpreted findings, with a personalised dose and duration and a rationale.

07

Nutrition plan

Individual dietary guidance targeted to the epigenetic profile.

08

Follow-up and retest

Structured follow-up, with an optional retest, typically after six months.

Well suited to people who want to assess their biological age and follow how changes in lifestyle and supplementation are reflected in markers of biological ageing.

Programme 02 · The pathway

A closed loop

A single epigenetic result offers a current insight into biological ageing. Its real value comes from following change over time. Repeating the measurement after a period of targeted intervention lets us assess whether changes in lifestyle and supplementation are reflected in markers of biological ageing.

01

Measure

Capillary blood sample and epigenetic analysis.

02

Interpret

Multidisciplinary review in clinical context.

04

Retest

Typically at six months; the protocol is adjusted.

03

Act

Protocol, personalised supplementation and nutrition plan, and follow-up.

Sampling where it suits the client

Chigra office
Workplace
Home

Samples and data are processed only with the client's explicit written consent, in line with the GDPR and Serbian data protection law.

06 — Programmes at a glance

Two programmes, one standard

Comparison of Chigra Panel and Chigra Epigenome
ItemChigra PanelChigra Epigenome
Health questionnaireIncludedIncluded
Biochemical panel, 33 parametersIncludedOptional
Epigenetic analysis—TruAge + TruHealth
SamplingVenous, at a lab of choice or DiaLabCapillary, at the office, work or home
Multidisciplinary interpretationIncludedIncluded
45-min in-person consultation, two or more specialistsIncludedIncluded
Personalised supplement protocolIncludedIncluded
Personalised nutrition planIncludedIncluded
Follow-up and review at one monthIncludedIncluded
ReassessmentRepeat biochemistry when indicatedRetest, typically at six months
Personalised supplement packageOptional add-onOptional add-on
Start with Panel for a first structured review of supplementation, metabolism and medicines.
Add Epigenome to measure biological ageing and track change over time.
How we work

Five steps to your protocol

From the first questionnaire to reassessment — clear, structured and tailored to you.

  1. 1

    Choose a package

    Profile, Panel or Epigenome

  2. 2

    Questionnaire

    About 10–15 minutes

  3. 3

    Consultation

    With our specialist team

  4. 4

    Your protocol

    Supplements and nutrition, in writing

  5. 5

    Follow-up

    With a reassessment date

Packages & prices

Choose the start that suits you

Prices include VAT. Laboratory analyses are paid to the laboratory.

To begin

Chigra Profile

7,900RSD

A 30-minute consultation, online or in person.

  • Health questionnaire
  • Consultation, 30 min
  • Personal protocol
Book (30 min)
Programme 01

Chigra Panel

15,000RSD

A 45-minute in-person consultation with at least two specialists.

  • Health questionnaire
  • Interpretation of the biochemical panel (33 parameters)
  • Personal protocol and nutrition plan
  • Follow-up through the first month
  • Review consultation at one month
Book (45 min)
Programme 02

Chigra Epigenome

Price coming soon

An epigenetic assessment of biological ageing.

  • DNA methylation analysis
  • Biological age and organ-system ageing
  • Telomere length estimate
  • Protocol and lifestyle plan
  • Retest
Notify me when available

The supplement package is an optional add-on — we email the price before preparation and delivery.

Personalised Chigra supplement package — a dark glass bottle labelled with the client's name, substance, dose and capsule count
07 — Optional, for both programmes

Personalised supplement package

Based on the protocol, we can prepare a personalised supplement package of carefully selected substances, in the recommended forms and doses, labelled with your name and delivered to your home address.

Evidence-based substances

A science-based selection of carefully chosen compounds.

One or three months

Supplied for one month or three, aligned with follow-up.

Delivered home

Sent to the client's address once the order is confirmed.

No obligation to buy

The protocol is complete and independent of buying supplements. Ordering them is entirely your choice.

08 — What your patient receives

The protocol – clear to the client, useful to the physician

Every protocol is clearly structured, so that the client understands the recommendations and their physician can review them and assess how they fit with existing therapy.

A man on a city street looking up and laughing

Supplement protocol

  • Substance and its form
  • Dose and regimen — how much, when, how
  • Duration
  • Rationale for this individual
  • Precautions and interactions with current medicines
  • Date of planned reassessment

Nutrition plan

  • Dietary priorities derived from the findings
  • Practical guidance for everyday meals
  • Food-first sources of key nutrients
  • Adjustments for medicines and conditions
  • Recommendations on physical activity and sleep
When supplementation is not indicated

We say so clearly and suggest next steps. Our programmes are built on expert assessment, interpretation of results and individual recommendations; supplementation is never assumed in advance and is recommended only when justified.

Shared with the treating physician

The protocol is sent to the client in writing. With the client's consent, we send it directly to the referring clinician.

09 — Working together · For clinicians

A simple referral pathway

For physicians and other healthcare professionals who wish to include our programmes in their practice.

  1. 01

    Identify

    A patient who self-supplements, takes several medicines or asks about prevention.

  2. 02

    Refer

    Share our contact details with the patient, or contact us directly. Recent laboratory results and current therapy help us understand their needs faster.

  3. 03

    Assess

    We run the agreed programme: measurement, interpretation and consultations.

  4. 04

    Report back

    With the patient's consent, you receive a summary of findings and the protocol.

  5. 05

    Continuity of professional collaboration

    Where findings call for further medical assessment, we refer the client to the appropriate specialist without delay.

Our commitments to you

  • No diagnosis, no change to prescribed therapy
  • Interaction review against the full medication list
  • Transparent evidence behind every substance
  • Written feedback, with patient consent
10 — The team

Different expertise, one standard of care

Clinical pharmacy, medical biochemistry, toxicology, pharmacokinetics and internal medicine at one table. We review every protocol from different professional perspectives to shape recommendations tailored to the individual.

Specialist team

Dr. Tamara Gojković, PharmD, PhD

Specialist in Medical Biochemistry

Co-founder

Dr. Milica Ćulafić, PharmD, PhD

Specialist in Clinical Pharmacy

Co-founder

Dr. Aleksandra Buha Đorđević

Toxicology · safety thresholds and exposure

Dr. Milica Miljković-Trailović

Medical Biochemistry · panel standards and quality

Dr. Stefan Stojković

Internal Medicine · Gastroenterology and Hepatology

Dr. Marija Jovanović

Pharmacokinetics · absorption, dose and timing

Advisory board

Dr. Sonja Šuvakov, MD, PhD

Scientist · cellular senescence and ageing biology

Dr. Keti Kasa, PharmD

Specialist in Nutrigenomics · gene–nutrient interactions

Dr. Violeta Vojinović-Ćulafić

Endocrinology · hormonal and metabolic health

Dr. Angelina Stevanović

Cardiology · cardiovascular risk

Dr. Nina Pejić

Internal Medicine

Booking

Book a consultation

Choose your package and a time that suits you. Confirmation and reminders arrive by email.

  1. 01

    Questionnaire

    Completed before the consultation and takes about 10–15 minutes. No payment at this step.

    Fill in the questionnaire ↗
  2. 02

    Package and time

    Profile is 30 minutes (online or in person). Panel is 45 minutes, in person, with at least two team members.

  3. 03

    Payment

    Online consultations are paid when booking. In-person consultations are paid at the office on the day.

  4. Bregalnička 3, Belgrade

    Email reminders 24 h and 2 h before your appointment. Times are shown in Belgrade time.

Pick a time

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Contact

Science.
Care.
You.

For partnerships, patient referrals or questions about our programmes — write to us.

Book a consultationWrite to us
Partnershipsinfo@chigrabio.com
OfficeChigra Bio DOO Beograd
Bregalnička 3, 11000 Belgrade, Serbia
Webchigrabio.com